Letha Manasulu is about identical twins Puppy and Lalli (Kutty Padmini) who accidentally meet and discover that they are sisters, separated due to their warring parents. They decide to switch places in order to unite their parents.

Two broken people, a Widow and a Wanderer helps a young couple while trying to live their lives.

Bhanumathi falls in love with Basavaraju, with whom her marriage was fixed earlier.